An aromatase inhibitor is a type of medication that works by blocking the enzyme aromatase, which plays a key role in the production of estrogen. Estrogen is a hormone that is primarily produced in the ovaries in premenopausal women and in the adrenal glands and fat tissues in postmenopausal women.
Aromatase inhibitors are commonly used in the treatment of hormone receptor-positive breast cancer, as these types of tumors rely on estrogen to grow and spread. By inhibiting aromatase and reducing estrogen levels in the body, these medications can help slow down or stop the growth of breast cancer cells.
There are two main types of aromatase inhibitors: steroidal and non-steroidal. Steroidal aromatase inhibitors work by permanently binding to the aromatase enzyme, while non-steroidal inhibitors work by reversibly binding to the enzyme. Both types of inhibitors are effective in reducing estrogen levels, but they may have different side effects and interactions with other medications.
Aromatase inhibitors are usually prescribed to postmenopausal women with hormone receptor-positive breast cancer, either as an adjuvant treatment after surgery or as a first-line therapy for metastatic breast cancer. These medications are typically taken orally in the form of a pill and may be used alone or in combination with other treatments such as chemotherapy or targeted therapy.
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Conclusion
In conclusion, it is important to carefully follow the recommended dosage instructions for aromatase inhibitors to ensure their effectiveness and minimize the risk of potential side effects. Consult with your healthcare provider for personalized guidance on the appropriate dosage for your specific needs.